Blood Clots Revamped for Acute and Chronic Wound Healing

Abigail Corrin

December 15, 2005
CLU - Richter Hall Ahmanson Science Building

Skin is the largest organ in the body forming a critical protective barrier to the external environment. During normal wound healing, a fibrin clot is formed within the first few minutes and is replaced with fibroblasts and other cells. This process leads to the rebuidling of dermal tissue on which the epidermal tissue is slowly rebuilt. In severe acute and chronic wounds dermal replacement materials are needed that mimic these processes. Current trends are to use scaffolds as structural substitutes as well as carriers for gorwth factors and cells for wound treatment. However, a basic understanding o the micrcrostructure of fibrin/collage constructs is not yet fully established.

Abigail Corrin
California Lutheran University

Abigail Corrin is currently a second year undergrad at California Lutheran University. She is majoring in Bioengineering/ Biochemistry - Molecular Biology with Highest Honors.

Recently, hhe gave a presentation at the 4th Annual California Tissue Engineering Meeting held at University of California, Irvine. After she obtains her undergraduate
degree, she will continue on to some form of graduate school.